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1.

Small RNAs are modified with N-glycans and displayed on the surface of living cells.

Flynn, Ryan A; Pedram, Kayvon; Malaker, Stacy A; Batista, Pedro J; Smith, Benjamin A H; Johnson, Alex G; George, Benson M; Majzoub, Karim; Villalta, Peter W; Carette, Jan E; Bertozzi, Carolyn R.

Cell; 184(12): 3109-3124.e22, 2021 06 10.

Artículo en Inglés | MEDLINE | ID: mdl-34004145

2.

Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions.

Flynn, Ryan A; Belk, Julia A; Qi, Yanyan; Yasumoto, Yuki; Wei, Jin; Alfajaro, Mia Madel; Shi, Quanming; Mumbach, Maxwell R; Limaye, Aditi; DeWeirdt, Peter C; Schmitz, Cameron O; Parker, Kevin R; Woo, Elizabeth; Chang, Howard Y; Horvath, Tamas L; Carette, Jan E; Bertozzi, Carolyn R; Wilen, Craig B; Satpathy, Ansuman T.

Cell; 184(9): 2394-2411.e16, 2021 04 29.

Artículo en Inglés | MEDLINE | ID: mdl-33743211

3.

Genetic Screens Identify Host Factors for SARS-CoV-2 and Common Cold Coronaviruses.

Wang, Ruofan; Simoneau, Camille R; Kulsuptrakul, Jessie; Bouhaddou, Mehdi; Travisano, Katherine A; Hayashi, Jennifer M; Carlson-Stevermer, Jared; Zengel, James R; Richards, Christopher M; Fozouni, Parinaz; Oki, Jennifer; Rodriguez, Lauren; Joehnk, Bastian; Walcott, Keith; Holden, Kevin; Sil, Anita; Carette, Jan E; Krogan, Nevan J; Ott, Melanie; Puschnik, Andreas S.

Cell; 184(1): 106-119.e14, 2021 01 07.

Artículo en Inglés | MEDLINE | ID: mdl-33333024

4.

The herpesvirus UL49.5 protein hijacks a cellular C-degron pathway to drive TAP transporter degradation.

Wachalska, Magda; Riepe, Celeste; Slusarz, Magdalena J; Graul, Malgorzata; Borowski, Lukasz S; Qiao, Wenjie; Foltynska, Michalina; Carette, Jan E; Bienkowska-Szewczyk, Krystyna; Szczesny, Roman J; Kopito, Ron R; Lipinska, Andrea D.

Proc Natl Acad Sci U S A; 121(11): e2309841121, 2024 Mar 12.

Artículo en Inglés | MEDLINE | ID: mdl-38442151

5.

Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression.

Zengel, James; Wang, Yu Xin; Seo, Jai Woong; Ning, Ke; Hamilton, James N; Wu, Bo; Raie, Marina; Holbrook, Colin; Su, Shiqi; Clements, Derek R; Pillay, Sirika; Puschnik, Andreas S; Winslow, Monte M; Idoyaga, Juliana; Nagamine, Claude M; Sun, Yang; Mahajan, Vinit B; Ferrara, Katherine W; Blau, Helen M; Carette, Jan E.

Nat Methods; 20(7): 1070-1081, 2023 07.

Artículo en Inglés | MEDLINE | ID: mdl-37291262

6.

MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.

Dovey, Cole M; Diep, Jonathan; Clarke, Bradley P; Hale, Andrew T; McNamara, Dan E; Guo, Hongyan; Brown, Nathaniel W; Cao, Jennifer Yinuo; Grace, Christy R; Gough, Peter J; Bertin, John; Dixon, Scott J; Fiedler, Dorothea; Mocarski, Edward S; Kaiser, William J; Moldoveanu, Tudor; York, John D; Carette, Jan E.

Mol Cell; 70(5): 936-948.e7, 2018 06 07.

Artículo en Inglés | MEDLINE | ID: mdl-29883610

7.

Nuclear accumulation of host transcripts during Zika Virus Infection.

Leon, Kristoffer E; Khalid, Mir M; Flynn, Ryan A; Fontaine, Krystal A; Nguyen, Thong T; Kumar, G Renuka; Simoneau, Camille R; Tomar, Sakshi; Jimenez-Morales, David; Dunlap, Mariah; Kaye, Julia; Shah, Priya S; Finkbeiner, Steven; Krogan, Nevan J; Bertozzi, Carolyn; Carette, Jan E; Ott, Melanie.

PLoS Pathog; 19(1): e1011070, 2023 01.

Artículo en Inglés | MEDLINE | ID: mdl-36603024

8.

SETD3 is an actin histidine methyltransferase that prevents primary dystocia.

Wilkinson, Alex W; Diep, Jonathan; Dai, Shaobo; Liu, Shuo; Ooi, Yaw Shin; Song, Dan; Li, Tie-Mei; Horton, John R; Zhang, Xing; Liu, Chao; Trivedi, Darshan V; Ruppel, Katherine M; Vilches-Moure, José G; Casey, Kerriann M; Mak, Justin; Cowan, Tina; Elias, Joshua E; Nagamine, Claude M; Spudich, James A; Cheng, Xiaodong; Carette, Jan E; Gozani, Or.

Nature; 565(7739): 372-376, 2019 01.

Artículo en Inglés | MEDLINE | ID: mdl-30626964

9.

Loquacious modulates flaviviral RNA replication in mosquito cells.

Shivaprasad, Shwetha; Weng, Kuo-Feng; Ooi, Yaw Shin; Belk, Julia; Carette, Jan E; Flynn, Ryan; Sarnow, Peter.

PLoS Pathog; 18(4): e1010163, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-35482886

10.

TMEM41B and VMP1 modulate cellular lipid and energy metabolism for facilitating dengue virus infection.

Yousefi, Meisam; Lee, Wai Suet; Yan, Biaoguo; Cui, Liang; Yong, Cythia Lingli; Yap, Xin; Tay, Kwan Sing Leona; Qiao, Wenjie; Tan, Dewei; Nurazmi, Nur Insyirah; Linster, Martin; Smith, Gavin J D; Lee, Yie Hou; Carette, Jan E; Ooi, Eng Eong; Chan, Kuan Rong; Ooi, Yaw Shin.

PLoS Pathog; 18(8): e1010763, 2022 08.

Artículo en Inglés | MEDLINE | ID: mdl-35939522

11.

PLA2G16 represents a switch between entry and clearance of Picornaviridae.

Staring, Jacqueline; von Castelmur, Eleonore; Blomen, Vincent A; van den Hengel, Lisa G; Brockmann, Markus; Baggen, Jim; Thibaut, Hendrik Jan; Nieuwenhuis, Joppe; Janssen, Hans; van Kuppeveld, Frank J M; Perrakis, Anastassis; Carette, Jan E; Brummelkamp, Thijn R.

Nature; 541(7637): 412-416, 2017 01 19.

Artículo en Inglés | MEDLINE | ID: mdl-28077878

12.

Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation.

Song, Yanhua; Hou, Gaopeng; Diep, Jonathan; Ooi, Yaw Shin; Akopyants, Natalia S; Beverley, Stephen M; Carette, Jan E; Greenberg, Harry B; Ding, Siyuan.

Nucleic Acids Res; 49(22): 12706-12715, 2021 12 16.

Artículo en Inglés | MEDLINE | ID: mdl-34791430

13.

Lipid droplets can promote drug accumulation and activation.

Dubey, Ramin; Stivala, Craig E; Nguyen, Huy Quoc; Goo, Young-Hwa; Paul, Antoni; Carette, Jan E; Trost, Barry M; Rohatgi, Rajat.

Nat Chem Biol; 16(2): 206-213, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-31932720

14.

Differential and convergent utilization of autophagy components by positive-strand RNA viruses.

Abernathy, Emma; Mateo, Roberto; Majzoub, Karim; van Buuren, Nick; Bird, Sara W; Carette, Jan E; Kirkegaard, Karla.

PLoS Biol; 17(1): e2006926, 2019 01.

Artículo en Inglés | MEDLINE | ID: mdl-30608919

15.

Genetic dissection of Flaviviridae host factors through genome-scale CRISPR screens.

Marceau, Caleb D; Puschnik, Andreas S; Majzoub, Karim; Ooi, Yaw Shin; Brewer, Susan M; Fuchs, Gabriele; Swaminathan, Kavya; Mata, Miguel A; Elias, Joshua E; Sarnow, Peter; Carette, Jan E.

Nature; 535(7610): 159-63, 2016 07 07.

Artículo en Inglés | MEDLINE | ID: mdl-27383987

16.

Improved Genome Editing through Inhibition of FANCM and Members of the BTR Dissolvase Complex.

de Alencastro, Gustavo; Puzzo, Francesco; Pavel-Dinu, Mara; Zhang, Feijie; Pillay, Sirika; Majzoub, Karim; Tiffany, Matthew; Jang, Hagoon; Sheikali, Adam; Cromer, M Kyle; Meetei, Ruhikanta; Carette, Jan E; Porteus, Matthew H; Pekrun, Katja; Kay, Mark A.

Mol Ther; 29(3): 1016-1027, 2021 03 03.

Artículo en Inglés | MEDLINE | ID: mdl-33678249

17.

RIP3 induces apoptosis independent of pronecrotic kinase activity.

Mandal, Pratyusha; Berger, Scott B; Pillay, Sirika; Moriwaki, Kenta; Huang, Chunzi; Guo, Hongyan; Lich, John D; Finger, Joshua; Kasparcova, Viera; Votta, Bart; Ouellette, Michael; King, Bryan W; Wisnoski, David; Lakdawala, Ami S; DeMartino, Michael P; Casillas, Linda N; Haile, Pamela A; Sehon, Clark A; Marquis, Robert W; Upton, Jason; Daley-Bauer, Lisa P; Roback, Linda; Ramia, Nancy; Dovey, Cole M; Carette, Jan E; Chan, Francis Ka-Ming; Bertin, John; Gough, Peter J; Mocarski, Edward S; Kaiser, William J.

Mol Cell; 56(4): 481-95, 2014 Nov 20.

Artículo en Inglés | MEDLINE | ID: mdl-25459880

18.

A memory of eS25 loss drives resistance phenotypes.

Johnson, Alex G; Flynn, Ryan A; Lapointe, Christopher P; Ooi, Yaw Shin; Zhao, Michael L; Richards, Christopher M; Qiao, Wenjie; Yamada, Shizuka B; Couthouis, Julien; Gitler, Aaron D; Carette, Jan E; Puglisi, Joseph D.

Nucleic Acids Res; 48(13): 7279-7297, 2020 07 27.

Artículo en Inglés | MEDLINE | ID: mdl-32463448

19.

RNA-protein interaction detection in living cells.

Ramanathan, Muthukumar; Majzoub, Karim; Rao, Deepti S; Neela, Poornima H; Zarnegar, Brian J; Mondal, Smarajit; Roth, Julien G; Gai, Hui; Kovalski, Joanna R; Siprashvili, Zurab; Palmer, Theo D; Carette, Jan E; Khavari, Paul A.

Nat Methods; 15(3): 207-212, 2018 03.

Artículo en Inglés | MEDLINE | ID: mdl-29400715

20.

Cracking the cell access code for the deadly virus VEEV.

Zengel, James; Carette, Jan E.

Nature; 588(7837): 223-224, 2020 12.

Artículo en Inglés | MEDLINE | ID: mdl-33208905

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